
Advanced Age And Fertility Challenges
Advanced age has a negative impact on sperm quality and integrity of DNA –
Age: Advanced paternal age (usually 40+) is linked to increased risk of miscarriage, autism, schizophrenia, and some genetic disorders.
DNA damage: Poor diet, smoking, alcohol, pollution, and stress can damage sperm DNA, potentially leading to developmental issues in the baby.
Epigenetic changes: Sperm from older men may carry epigenetic marks that influence gene expression in the developing fetus—potentially affecting metabolism, brain development, and aging.
Longer time to conception: Studies show it can take longer to conceive with an older father, even if the female partner is young and healthy.
Pregnancy complications: higher miscarriage rates-Risk increases due to DNA damage in sperm. Stillbirth – Some studies suggest a slightly increased risk of stillbirth.
Image credit: Image by Victoria from Pixabay (Free to use under Pixabay content license)
Author: Sumana Rao | Posted on: June 23, 2025
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